Could This Breast Cancer Research Make a Difference. A Look at the Stefanie Spielman Fund’s Impact

Could This Breast Cancer Research Make a Difference. A Look at the Stefanie Spielman Fund’s Impact

Introduction to Stefanie Spielman and her battle with breast cancer

In the late 1990s, Stefanie Spielman was a beloved anchor and reporter for the local CBS affiliate in Columbus, Ohio. She seemed to have it all – a successful career, loving family, and bright future. That changed in 1998 when Stefanie was diagnosed with breast cancer at the age of 30. It was a shock to Stefanie and her community. She had no family history of breast cancer and seemed too young to receive such a devastating diagnosis.

Stefanie approached her battle with breast cancer with fierce determination and courage. She allowed news cameras to document her journey to show the world what it was like to fight this disease as a young woman. She endured multiple surgeries, radiation, and chemotherapy over the next decade. During this time, Stefanie became an advocate for breast cancer awareness and research.

The Spielman family steps up during Stefanie’s fight

Stefanie’s husband, Chris Spielman, was a former Ohio State and NFL football star. He stood steadfastly by Stefanie’s side during her battle. In 1999, Chris and Stefanie established the Stefanie Spielman Fund for Breast Cancer Research. Their goal was to raise money to advance breast cancer research and help find a cure. The Spielman family rallied together to grow the fund through golf tournaments, fundraising events, and engaging the enthusiastic Ohio State fan base.

Donations pour in to support Stefanie’s cause

As Stefanie’s story spread, donations began pouring in from across Ohio and the country. Fans were moved by Stefanie’s courage and wanted to join the fight against breast cancer. Schools, businesses, and individuals stepped up with creative fundraisers. Stefanie’s warm personality and unwavering spirit inspired people to give generously. Within a few years, the fund raised millions of dollars.

The Stefanie Spielman Fund’s impact on breast cancer research

The Stefanie Spielman Fund has been a game-changer for breast cancer research. To date, the fund has raised over $25 million. This has allowed Ohio State’s Comprehensive Cancer Center to make great strides in understanding, detecting, and treating breast cancer.

Cutting-edge clinical trials test new treatments

Clinical trials allow researchers to test promising new therapies with volunteer patients. However, clinical trials are expensive to conduct. The Spielman Fund has provided critical funding to open clinical trials that otherwise may not have occurred. Patients today can access experimental treatments in Columbus that previously would have only been available in larger cities.

Improving diagnosis and reducing side effects

Researchers at Ohio State are studying ways to more accurately diagnose breast cancer and detect it earlier when it is most treatable. Other studies are focused on reducing side effects from chemotherapy, radiation, and surgery. Living with breast cancer can be physically and emotionally taxing. Improving quality of life is an important goal.

Prevention and reducing risk

While the cause of breast cancer is still unknown, researchers funded by the Spielman Fund are looking for ways to prevent the disease. Studies examine lifestyle factors, genetics, and molecular pathways that influence breast cancer risk. This research will help identify who is at high risk and how to reduce that risk.

Empowering the next generation of researchers

The Spielman Fund awards grants to recruit talented young breast cancer researchers to Ohio State. Bringing fresh perspectives empowers the search for new discoveries. These grants also allow doctors to devote time specifically to breast cancer research while still caring for patients.

The Stefanie Spielman Breast Cancer Center offers comprehensive care

In addition to funding research, donations to the Spielman Fund supported the creation of the Stefanie Spielman Comprehensive Breast Center at Ohio State. This facility opened in 2010 to provide coordinated, patient-focused breast cancer care.

One-stop facility for breast cancer patients

Patients can receive mammograms, biopsies, surgeries, chemotherapy, radiation, counseling, and survivorship care all in one location. This convenience improves continuity of care during a difficult time. The facility was designed with patient comfort in mind.

Multidisciplinary approach to treatment

Doctors from surgical oncology, medical oncology, radiation oncology, radiology, pathology, psychology, and genetics hold clinics in the center. Patients can meet their whole care team in one visit. This facilitates developing customized treatment plans for each patient.

Latest technology for accurate diagnosis

The Breast Center offers advanced screening and diagnostic equipment. This includes 3D mammography, MRI breast imaging, ultrasound, and minimally invasive biopsy options. Patients benefit from earlier detection thanks to this technology.

Carrying on Stefanie’s legacy

Tragically, Stefanie Spielman passed away from breast cancer in 2009 at the age of 42. However, her legacy lives on through the fund, breast center, and countless lives touched by her courageous spirit. The grassroots effort started by the Spielmans continues to raise millions annually. Ohio State researchers are making breakthroughs thanks to this ongoing support.

Donations to the Stefanie Spielman Fund empower progress in the fight against breast cancer. With continued community support, Ohio State researchers are advancing knowledge and bringing us closer to a future without this devastating disease.

Overview of the Stefanie Spielman Fund for Breast Cancer Research

The Stefanie Spielman Fund for Breast Cancer Research was established in 1999 by Stefanie Spielman and her husband Chris Spielman. Stefanie was battling breast cancer and the couple wanted to make a difference for others fighting this disease.

The fund started small through grassroots community fundraising efforts in Stefanie and Chris’s hometown of Columbus, Ohio. Local schools held penny drives, businesses hosted charity golf outings, and Ohio State fans poured donations into collection boxes at football games. As Stefanie bravely shared her story, support for the fund gained momentum.

How donations to the fund are used

All money raised by the Spielman Fund goes directly to breast cancer research at the Ohio State University Comprehensive Cancer Center. Donations support various needs:

• Funding cutting-edge research projects
• Recruiting top breast cancer scientists
• Purchasing advanced laboratory equipment
• Launching clinical trials of new treatments
• Covering research program expenses

Having a dedicated funding source empowers Ohio State researchers to pursue innovative, high-impact studies that can accelerate progress against breast cancer.

Fund oversight ensures donor wishes are fulfilled

The Spielman Fund is managed through the Columbus Foundation. This community foundation provides financial management services to ensure donations are used as intended. Additionally, an advisory panel reviews grant applications to select the most promising breast cancer research projects to support.

The fund honors Stefanie Spielman’s legacy by directing every dollar raised to scientific discovery at Ohio State. This oversight provides confidence to donors that their contributions make a real difference.

Key achievements from Spielman Fund research

In two decades, the Spielman Fund has advanced breast cancer research by leaps and bounds. Some key achievements include:

Breast cancer gene identification

Studies funded by the Spielman Fund were among the first to identify mutations in genes like BRCA1 and BRCA2 that increase breast cancer risk. This breakthrough enables improved genetic testing and counseling for high-risk patients.

Better risk prediction

Researchers developed statistical models that more accurately predict a woman’s risk for developing breast cancer. This allows for tailored screening and prevention strategies based on each patient’s risk profile.

Novel imaging techniques

New breast imaging approaches were devised through Spielman grants, including molecular breast imaging for women with dense breast tissue. This allows doctors to “see” small tumors that might be hidden on a mammogram.

The Spielman Fund empowers Ohio State to fast-track scientific findings from the lab to benefit patients in the clinic. Through steadfast community support, progress continues to be made in the fight against breast cancer.

The importance of funding breast cancer research

Breast cancer is the most common cancer diagnosis among American women, with over 280,000 new cases each year. It is also the second leading cause of cancer death for women. More funding is critically needed to change these sobering statistics.

Financial roadblocks hinder research

Government sources like the National Institutes of Health provide significant research funding. However, competition for federal grants is fierce. Only a small fraction of proposals receive backing. There are simply not enough resources to pursue every promising lead.

Pharmaceutical companies tend to fund late-stage drug studies with profit potential. But early conceptual work often requires philanthropic support to get off the ground.

How donations empower discoveries

Charitable funds like the Spielman Fund fill critical funding gaps. Donations allow scientists to think outside the box and follow unexplored pathways. Having financial flexibility enables high-risk, high-reward projects that could be transformative.

Gifts also facilitate collaboration and idea sharing. Researchers can come together to solve problems in new ways. Funds can be deployed rapidly when needs arise.

The ripple effects of philanthropic support

Each discovery lays groundwork for future advances. For example, understanding cancer genetics can lead to improved screening and personalized medicine. Supporting one promising scientist early in their career can lead to breakthroughs for decades to come.

Donors often find motivation in wanting to fund urgent, cutting-edge research. Their generosity sparks momentum and accelerates the discovery cycle from lab to patient care.

Ultimately, lives are saved thanks to the foresight and compassion of those who give to fuel progress. Breast cancer research needs sustained support to keep improving patient outcomes well into the future.

Key achievements from research funded by the Spielman Fund

The Stefanie Spielman Fund has provided critical support for impactful breast cancer research at Ohio State’s Comprehensive Cancer Center. Here are some key achievements made possible by donations to the fund:

Genetic mutations linked to breast cancer risk

Studies funded by the Spielman Fund were among the first to identify mutations in the BRCA1 and BRCA2 genes that dramatically increase a woman’s lifetime risk of developing breast cancer. This breakthrough enabled improved genetic testing to identify high-risk women needing enhanced screening.

Novel imaging techniques detect smaller tumors

Researchers pioneered new breast imaging approaches such as molecular breast imaging, which uses a radioactive tracer to pinpoint tumors. This allows detection of smaller cancers not visible on mammography, especially in women with dense breasts.

Reducing surgery’s impact on lymphedema

Lymphedema, chronic arm swelling due to lymph node removal, impacts up to 40% of breast cancer survivors. Spielman-funded research led to guidelines sparing underarm lymph nodes during surgery when possible, reducing lymphedema risk.

Elucidating racial disparities in breast cancer

Studies found biological differences in breast tumors between African American and white women, helping explain higher mortality rates among African Americans. This guides treatment tailored to each patient’s tumor profile.

Improving risk prediction with statistics

Researchers developed new statistical models incorporating clinical and genetic factors that more precisely estimate a woman’s risk of developing breast cancer. This enables personalized screening and prevention strategies.

Pioneering work in cancer survivorship

Spielman funding advanced research into the long-term effects of breast cancer treatment. Findings led to interventions to enhance quality of life after cancer, like exercise, diet, and stress reduction programs.

Donations to the Spielman Fund have accelerated progress against breast cancer through high-impact research. This work continues, bringing us steps closer to a future without this disease.

Spotlight on the Stefanie Spielman Breast Cancer Center

In addition to fueling research, the Stefanie Spielman Fund realized Stefanie’s dream of creating a dedicated breast cancer treatment facility. The Stefanie Spielman Comprehensive Breast Center opened at Ohio State in 2010.

One-stop coordinated care

The Breast Center provides a full spectrum of services including screening, diagnosis, treatment, genetics, counseling, and wellness programs. Patients can receive coordinated care efficiently in one location. The facility boasts a warm, supportive environment for women and families.

Multidisciplinary breast cancer experts

The Breast Center brings together breast radiologists, surgeons, medical/radiation oncologists, pathologists, plastic surgeons, and other specialists. Patients benefit from a unified team approach. Doctors collaborate closely to develop treatment plans tailored to each woman’s specific needs.

Access to clinical trials

As an academic medical center, Ohio State offers patients access to leading-edge clinical trials. The Breast Center facilitates connecting eligible patients to trials of novel therapies not widely available elsewhere. Participating in research is entirely voluntary.

Top-tier diagnostic capabilities

The Breast Center provides every advanced screening technology including digital mammography, breast MRI, ultrasound, and breast-specific gamma imaging. Radiologists specialize exclusively in breast imaging. Minimally invasive biopsy options reduce complications.

Focus on wellness and survivorship

Services extend beyond medical treatment to address quality of life before, during, and after cancer. Support programs address exercise, nutrition, pain management, lymphedema prevention, emotional health, breast reconstruction, and more. The Breast Center empowers survivors.

Fulfilling Stefanie Spielman’s vision, the Breast Center delivers comprehensive patient-centered care under one roof. Donations to the Spielman Fund helped make this invaluable community resource a reality.

Cutting-edge clinical trials made possible by donations

Clinical trials allow researchers to test exciting new therapies and technologies on volunteer patients. However, trials require significant funding that research grants don’t always provide. Donations have enabled the launch of cutting-edge breast cancer trials at Ohio State.

Testing new targeted therapies

Spielman funds support testing targeted drugs that attack specific molecules involved in cancer growth. For example, trials provide access to the latest immunotherapy drugs harnessing the body’s immune system against tumors.

Optimizing treatment combinations

Researchers can use trials to figure out the best drug cocktails and optimal sequencing. Testing combinations may allow lower doses with fewer side effects. Trials also evaluate adding newer drugs to standard regimes.

Novel breast reconstruction techniques

New approaches to breast reconstruction after mastectomy are trialed to improve outcomes. Examples include nipple-sparing mastectomy, fat grafting, acellular dermal matrix slings, and innovative flap techniques to recreate natural-looking breasts.

Offering hope when other options end

For patients with advanced breast cancer that continues growing despite all standard treatments, phase I trials provide access to experimental drugs not yet approved. This offers hope and closely monitors to ensure safety.

Participating in clinical trials requires courage and hope. Donors empower trials so more patients can potentially benefit from new discoveries.

Ongoing support is key to sustain the cancer center’s robust clinical trials program at the forefront of breast cancer care.

Improving quality of life for breast cancer patients

Surviving breast cancer involves more than just eradicating tumors. The treatments needed to save lives can seriously impact quality of life during and after cancer. Research funded by the Spielman Fund aims to improve survivorship.

Managing treatment side effects

Studies explore interventions to minimize treatment side effects like pain, fatigue, nerve damage, and lymphedema. Therapies such as exercise, acupuncture, massage, and counseling teach patients self-care techniques. This empowers women coping through difficult treatments.

Innovations in breast reconstruction

New technologies and surgical techniques are tested to optimize cosmetic outcomes after mastectomy. Goals include maintaining natural breast shape, nipple sensation, and symmetry. Reconstruction greatly benefits self-esteem for many survivors.

Enhancing emotional well-being

A breast cancer diagnosis takes both physical and emotional tolls. Researchers develop support programs to help women cope with anxiety, depression, fear of recurrence, relationship disruptions, and altered body image. Support groups connect survivors facing shared struggles.

Improving survivor nutrition and fitness

Clinical trials provide structured diet and exercise interventions during and after treatment. Healthy lifestyle changes help counteract treatment effects like weight gain, fatigue, and reduced stamina and bone density. Active survivors often have better prognoses.

Donations fund innovative programs and research so survivors can reclaim fulfilling lives after cancer. Healing encompasses more than the physical – it is an ongoing journey of self-care and hope.

Continued investments in survivorship initiatives through the Spielman Fund better tomorrow’s outcomes for the next generation of patients.

Advancements in early detection and diagnosis

Detecting breast cancer at its earliest stages dramatically improves survival. Donations to the Spielman Fund empower research into enhanced breast cancer screening and diagnostic technologies.

Developing next-generation mammography

Funded projects refined 3D tomosynthesis, a mammogram technique producing detailed, layered images of the breast. This allows radiologists to distinguish harmless overlaps from potential tumors.

Supplemental screening tools

Researchers study supplemental tests like ultrasound, MRI, and molecular breast imaging to be used along with mammograms. This improves detection for women with dense or high-risk breasts where tumors can be obscured.

Artificial intelligence for screening

Scientists collaborate with engineers to develop AI systems to analyze mammogram images. Computer models learn to identify features predictive of cancer, serving as “second readers” to improve radiologists’ accuracy.

Minimally invasive biopsy options

Improved biopsy needles, localization, and imaging methods allow sampling suspicious areas with minimal discomfort, scarring, and recovery time. This facilitates prompt, accurate breast cancer diagnosis.

Thanks to Spielman funding, potentially life-saving screening and diagnostic advancements emerge from Ohio State research labs to become standards of care.

Research into reducing treatment side effects

When someone hears the words “breast cancer,” it’s easy to feel overwhelmed and worried. After all, breast cancer is one of the most common cancers diagnosed in women. Thankfully, treatment options and survivorship rates continue to improve. However, while treatments like chemotherapy and radiation therapy are often life-saving, they can also cause difficult side effects. Researchers are actively looking for ways to maximize treatment effectiveness while minimizing negative impacts on patients’ quality of life.

One organization at the forefront of this effort is the Stefanie Spielman Fund for Breast Cancer Research. Established in 2003, this fund honors Stefanie Spielman, wife of former Ohio State University football coach Chris Spielman. Stefanie battled breast cancer four times before passing away in 2009. During her fight, she became dedicated to raising awareness and supporting critical research.

The Stefanie Spielman Fund is housed at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute. With community donations, the fund has been able to support over $25 million in breast cancer research projects. The fund’s mission is to find cures and improve care for breast cancer patients, with a focus on minimizing treatment side effects. Some key areas of research for the fund include:

Preventing hair loss

Hair loss is one of the most emotionally difficult side effects of chemotherapy. It can negatively impact a patient’s body image and self-esteem. The Spielman Fund has supported projects investigating cooling cap therapies that constrict blood vessels in the scalp during chemo. This reduces the amount of chemo agents reaching hair follicles, preventing hair loss. Researchers are also exploring medications that could stop hair loss, such as a JAK inhibitor drug used for rheumatoid arthritis.

Reducing nausea and vomiting

Nausea and vomiting are very common during chemo and radiation treatments. These symptoms can lead to dehydration, weight loss, and nutritional deficits. The Spielman Fund has helped study the anti-nausea drug aprepitant in breast cancer patients. Researchers found it was significantly more effective than standard drugs for chemotherapy-induced nausea. The fund also supports continued research on optimal anti-nausea drug combinations to provide patients the greatest relief.

Lessening cognitive problems

Many breast cancer survivors report experiencing “chemo brain” – cognitive problems like memory and concentration issues after treatment. It’s unclear what causes chemo brain, but studies suggest chemotherapy drugs may impact brain cells and networks. With Spielman Fund support, researchers are investigating the biological basis for chemo brain. The fund also helps study behavioral interventions, like memory training exercises, that could help patients manage cognitive changes.

Reducing pain and neuropathy

Some chemo drugs can damage peripheral nerves, causing extremity pain, numbness, and tingling. Painful neuropathy can significantly impact quality of life during and after breast cancer treatment. Researchers with Spielman Fund grants are actively seeking ways to prevent neuropathy. Strategies include vitamin B6 supplementation to mitigate nerve damage and Omega-3 fatty acids to reduce inflammation and neuropathy symptoms. Acupuncture is also being studied as a therapy to potentially reduce neuropathy pain.

Improving sleep quality

Between hot flashes, nausea, neuropathy pain, and anxiety, sleep disturbances are very common in breast cancer patients. Poor sleep takes a major toll both during and after treatment. Researchers supported by the Spielman Fund are analyzing the sleep issues faced by breast cancer patients receiving hormone therapy. The goal is to identify targets for future interventions to improve sleep quality in this population.

In addition to critical research, the Stefanie Spielman Fund also supports patient assistance initiatives. This includes a specialty pharmacy program that provides free medications to eligible breast cancer patients. There is also a wig bank operated in coordination with the American Cancer Society to give wigs to breast cancer patients dealing with hair loss.

While Stefanie Spielman tragically lost her own battle with breast cancer, her legacy lives on through the fund’s work. In over 15 years, the organization has made significant impacts in reducing treatment side effects and improving quality of life for breast cancer patients and survivors. With continued community support, the fund can help turn breast cancer into a treatable, chronic condition that patients can manage long-term.

The Stefanie Spielman Fund’s research provides real hope that one day breast cancer treatments will be highly effective while minimizing burdensome side effects. This work embodies Stefanie’s spirit of compassion and perseverance. The fund’s research successes demonstrate that the collective efforts of a community can drive progress against even the most formidable disease. While there is still much work to be done, the Stefanie Spielman Fund’s impact so far gives breast cancer patients and researchers reason to be optimistic about the future.

Seeking ways to prevent breast cancer

Breast cancer remains one of the most common cancers affecting women today. In 2023 alone, over 300,000 new cases of invasive breast cancer are expected to be diagnosed. While treatment options have improved dramatically, a diagnosis of breast cancer still evokes fear and uncertainty. What if there was a way to prevent breast cancer from developing in the first place?

Groundbreaking research funded by organizations like the Stefanie Spielman Fund for Breast Cancer Research aims to do just that—stop breast cancer before it starts. The Fund was established in 2004 by Stefanie Spielman and her husband Chris Spielman, a former Ohio State and NFL linebacker. Stefanie passed away from breast cancer in 2009 at the age of 42, but her legacy lives on through the Fund’s tireless work to eradicate this disease.

Understanding the origin of breast cancer

To prevent breast cancer, scientists first need to understand how and why it develops in the first place. Breast cancer arises when genetic mutations occur that allow cells in the breast to grow and divide uncontrollably. The Stefanie Spielman Fund supports research delving deep into the molecular underpinnings of how cancer originates and progresses.

For example, Dr. Zhenghe John Wang at The Ohio State University is using Fund resources to study how postpartum breast cells differ from cancerous cells. During pregnancy, breast tissue changes dramatically in preparation for lactation. After giving birth, these cells are remodeled back to a pre-pregnant state. However, some cells retain traces of the pregnant state. Intriguingly, overexpression of genes active in pregnancy is also seen in breast cancer. Understanding how pregnancy transforms breast cells may thus provide insight into how cancer develops.

Can breast cancer risk be predicted?

Breast cancer does not arise overnight. It often takes years, even decades, for enough mutations to accumulate to transform a healthy cell into a cancerous one. If women at high risk for breast cancer could be identified early, then preventive measures could be taken.

The Spielman Fund supports multiple projects examining breast cancer risk and prevention. Dr. Electra Paskett at The Ohio State University College of Medicine received a grant to study mammography screening rates in rural Appalachian women. This population has a disproportionately high mortality rate from breast cancer. By analyzing barriers to screening, Dr. Paskett aims to find ways to improve early detection and save lives.

Other researchers are taking a more direct approach by developing models to predict an individual’s breast cancer risk based on their genetics and lifestyle. For example, Dr. Amanda Toland at Ohio State is identifying genetic markers that place certain women at higher risk. This allows preventive measures to be targeted to those who would benefit most.

Can we develop ways to prevent breast cancer?

Understanding breast cancer risk factors is invaluable, but the ultimate goal is preventing cancer from ever occurring. The Stefanie Spielman Fund is committed to researching breast cancer prevention strategies.

One major focus is on anti-hormone drugs called selective estrogen receptor modulators (SERMs). Estrogen promotes the growth of many breast cancers, so blocking its effects may stop cancer before it can gain a foothold. Dr. Tzonelia Munnerlyn at Ohio State is exploring whether SERMs like tamoxifen and raloxifene can reduce breast cancer risk in high-risk women like BRCA mutation carriers.

Studies examining diet and exercise also hold promise. Dr. Electra Paskett is leading a randomized trial investigating whether weight loss through diet and exercise can modulate breast cancer biomarkers in both blood and breast tissue. Confirming that these interventions directly impact cancer risk could lead to lifestyle recommendations that empower women to take control of their health.

Continuing Stefanie’s legacy

The cutting-edge research described above underscores the momentum behind discovering ways to prevent breast cancer, not just treat it. This work is fueled by generous donors and fundraising events like the Stefanie Spielman Classic golf tournament.

While Stefanie tragically lost her own battle with breast cancer, her legacy continues to inspire hope. Because of support from the Stefanie Spielman Fund, researchers are making progress uncovering breast cancer’s origins and weaknesses. The Fund’s unwavering commitment to eradicating this disease ensures that breakthroughs are within reach. There is a future on the horizon where fewer mothers, daughters, and sisters will have to face a devastating breast cancer diagnosis.

Stefanie once said, “If you are diagnosed with breast cancer, or any cancer…you need to know that there is hope.” The promising research supported by her Fund represents that hope, bringing us steps closer to making breast cancer a preventable disease.

Pursuing a future without breast cancer

Breast cancer remains a devastating disease, with over 300,000 women receiving an invasive breast cancer diagnosis each year. Treatment options have certainly advanced, but the physical and emotional toll of breast cancer still weigh heavily. What if there was a way to erase breast cancer from the equation altogether?

Organizations like the Stefanie Spielman Fund for Breast Cancer Research aim to make that vision a reality by furthering our understanding of how breast cancer originates and progresses. The Fund was started in 2004 by Stefanie Spielman and her husband Chris, a former Ohio State and NFL football player. Though Stefanie ultimately passed away from breast cancer in 2009, the work of her namesake Fund continues to propel groundbreaking discoveries that could lead to a future free of this disease.

Probing breast cancer’s origins

To prevent breast cancer from occurring, researchers first need to unravel exactly how and why it arises in the first place. Breast cancer develops due to genetic changes that allow breast cells to abnormally divide and grow out of control. The Fund provides critical resources enabling scientists to dig deep into the intricate molecular underpinnings of how normal breast cells transform into cancer.

For instance, Dr. Zhenghe John Wang at Ohio State is utilizing Fund support to compare postpartum breast cells to cancerous ones. During pregnancy, breast tissue undergoes dramatic changes to enable milk production. Afterwards, extensive tissue remodeling returns the breast to a pre-pregnant state. Intriguingly though, some cells retain traces of the pregnant profile. Since genes activated in pregnancy are also overexpressed in breast cancer, understanding postpartum breast cell behavior could provide pivotal insights into how cancer emerges.

Identifying those at highest risk

Breast cancer does not form instantaneously but rather accumulates mutations over many years, even decades. If women at increased risk could be recognized early on, preventive actions could be implemented to potentially thwart cancer from ever taking hold.

The Spielman Fund supports multiple researchers working to improve breast cancer risk assessment and prevention. For example, Dr. Electra Paskett at Ohio State’s College of Medicine was awarded a grant to analyze mammography rates among rural Appalachian women, who suffer disproportionately high breast cancer mortality. By determining barriers to screening in this population, Dr. Paskett seeks to boost early detection and save lives.

Other scientists, like Dr. Amanda Toland at Ohio State, take a more targeted approach by pinpointing genetic markers that predispose certain women to heightened breast cancer risk. This enables tailored prevention strategies to focus on those who stand to benefit most.

Exploring breast cancer prevention strategies

Identifying risk factors provides key insights, but the ultimate prize is preventing breast cancer from ever taking hold. The Stefanie Spielman Fund steadfastly invests in researching breast cancer prevention techniques.

A major emphasis is on anti-hormone medications called selective estrogen receptor modulators (SERMs). Since estrogen spurs the growth of many breast cancers, blocking its effects may thwart cancer genesis. Dr. Tzonelia Munnerlyn at Ohio State is investigating whether SERMs like tamoxifen and raloxifene can reduce breast cancer risk, especially in high-risk women such as BRCA mutation carriers.

Studies on lifestyle changes also show promise. Dr. Electra Paskett is conducting a randomized trial examining if diet-induced weight loss can favorably alter breast cancer biomarkers in blood and breast tissue. Confirming that interventions like diet and exercise directly lower cancer risk could lead to lifestyle recommendations that empower women to take control.

Continuing the inspirational legacy

The trailblazing research described above highlights the great momentum behind discovering ways to prevent breast cancer, not just treat it. This work is fueled by generous donors and events like the Stefanie Spielman Classic golf outing.

Though Stefanie ultimately succumbed to breast cancer, her legacy remains a source of hope. Thanks to the Stefanie Spielman Fund’s unwavering commitment to eradicating this disease, researchers are uncovering breast cancer’s vulnerabilities and how to exploit them. The Fund’s stalwart support ensures scientific breakthroughs are within reach, bringing us steps closer to making breast cancer preventable. There is a future on the horizon where fewer mothers, daughters, and sisters will have to endure a devastating breast cancer diagnosis.

In Stefanie’s words, “If you are diagnosed with breast cancer, or any cancer…you need to know that there is hope.” The groundbreaking research made possible by her namesake Fund represents that hope, as we collectively seek a future liberated from the specter of breast cancer.

Fundraising events supporting the Spielman Fund

Since its inception in 2004, the Stefanie Spielman Fund for Breast Cancer Research has been relentlessly pursuing ways to eradicate breast cancer. But this vital work would not be possible without dedicated supporters and successful fundraising efforts.

The Fund was established by Stefanie Spielman and her husband Chris after Stefanie’s first breast cancer diagnosis. Tragically, Stefanie ultimately lost her battle with this disease in 2009 at age 42. However, her legacy lives on through the Fund’s tireless efforts to unlock the secrets of breast cancer and stop it before it starts.

Annual fundraising events

One major annual event is the Stefanie Spielman Classic golf outing, held in late summer at The Ohio State University Golf Club. This tournament brings together over 200 participants, including college friends and former teammates of Chris Spielman. Since its inception, the Classic has raised over $1.2 million for cutting-edge breast cancer research.

Another yearly tradition is the Stefanie’s Champions luncheon, which honors outstanding community members who exemplify Stefanie’s spirit of courage and compassion. This inspirational event has raised over $2 million for the Fund since 2013.

Smaller gatherings like birthday and anniversary tributes also regularly pop up, allowing donors to celebrate Stefanie’s life while funding important research advancements. No matter the size or type, these events keep Stefanie’s uplifting legacy alive.

Third party fundraisers

In addition to its own signature events, the Fund benefits from third party fundraisers organized independently. These range from casual gatherings like bake sales and yoga classes to more elaborate galas and races.

For instance, Pelotonia is an annual cycling event through Ohio that has directed over $200 million to cancer research at Ohio State since 2009, including substantial sums to the Spielman Fund. Stefanie’s supportive and determined spirit lives on through these riders tackling mile after mile in her honor.

High school volleyball tournaments have also been a creative way for teams to compete while raising money for the Fund. These events allow young athletes to rally around Stefanie’s story and make a difference through sport, just as she did.

Individual supporters

While events bring together communities, the Fund also relies on the compassion of individual supporters. Online donations in honor of birthdays, anniversaries, and other milestones provide a steady stream of resources for the Fund.

Many supporters become dedicated regular contributors through monthly or annual gifts. To date, over 5,000 donors have given $1,000 or more to fuel the Fund’s lifesaving mission of eradicating breast cancer.

Workplace giving programs have also been instrumental. Ohio State faculty and staff have donated over $1 million through payroll deductions so far. Businesses like L Brands, OSU’s Wexner Medical Center, and BMW Financial Services also encourage employee gifts to the Fund.

Furthering Stefanie’s inspirational legacy

While taken far too soon by breast cancer, Stefanie Spielman remains a source of hope and strength. Fundraising events held in her honor allow communities to come together, celebrate her vibrant spirit, and create meaningful change.

Every dollar raised through these collective efforts supports scientific breakthroughs that will bring us closer to the day when no one has to face the devastation of a breast cancer diagnosis. By supporting the Stefanie Spielman Fund, we can help realize Stefanie’s dream of eradicating this disease once and for all.

How donations make a meaningful difference

Since 2004, the Stefanie Spielman Fund for Breast Cancer Research has tirelessly pursued ways to eradicate breast cancer. But this vital work depends on the generosity of donors to turn vision into reality.

The Fund was established by Stefanie Spielman and her husband Chris after Stefanie’s first breast cancer diagnosis. Though Stefanie ultimately succumbed to the disease in 2009, the Fund remains committed to deciphering how breast cancer starts and progresses in order to develop prevention strategies.

Supporting groundbreaking research

Donations to the Fund provide essential resources for researchers seeking to unravel the intricacies of breast cancer genesis and growth. Studies investigating topics like genes linked to cancer risk, effects of pregnancy on breast cells, and anti-hormone prevention drugs are illuminating new directions for intervention.

For example, Dr. Electra Paskett at Ohio State’s College of Medicine received a grant to improve mammography screening rates in underserved Appalachian women. By determining barriers to early detection, she aims to curtail breast cancer deaths in this vulnerable population.

Donations also facilitate innovative projects like Dr. Amanda Toland’s work identifying genetic markers that predict breast cancer risk. This enables prevention to be targeted to those most likely to benefit.

Propelling progress through events

Fundraising events enable communities to jointly fuel progress. The annual Stefanie Spielman Classic golf tournament has raised over $1.2 million since its inception. Meanwhile, the Stefanie’s Champions luncheon has generated over $2 million for research since 2013.

The Fund also benefits from third party events like Pelotonia bike races, high school volleyball tournaments, and small gatherings on birthdays or anniversaries. These collective efforts channel Stefanie’s inspirational spirit into scientific advancement.

Consistency through individual giving

While events provide periodic infusions, consistent individual donors are the Fund’s backbone. Over 5,000 supporters have contributed $1,000 or more to-date.

Many donors commit to recurring monthly or annual gifts to ensure a steady flow of resources. Workplace giving further bolsters consistency, with Ohio State faculty and staff donating over $1 million so far through payroll deductions.

Compassionate supporters also make one-time donations in honor of special occasions like birthdays and weddings. These thoughtful contributions celebrate milestones while funding milestone breakthroughs.

Turning dollars into scientific discoveries

Thanks to this broad base of support, the Fund is making tremendous strides toward understanding how to thwart breast cancer. Breakthroughs on the horizon include refining risk prediction, developing preventive medications, and formulating lifestyle recommendations to reduce cancer susceptibility.

While taken too soon by breast cancer, Stefanie Spielman’s hopeful legacy persists through donors collectively working toward the day when no one has to face this devastating diagnosis. By supporting the Fund that bears her name, we can transform generosity into groundbreaking research to eradicate breast cancer once and for all.

Over $25 million raised to date by the Fund

Since its founding in 2004, the Stefanie Spielman Fund for Breast Cancer Research has raised over $25 million to support groundbreaking research into eradicating breast cancer. This incredible achievement underscores the power of an inspiring legacy and a community united behind a cause.

The Fund was established by Stefanie Spielman and her husband Chris after Stefanie’s first breast cancer diagnosis at 30 years old. Though Stefanie ultimately lost her battle with the disease in 2009, the Fund remains fiercely committed to deciphering how breast cancer originates and progresses in order to develop prevention strategies.

Early fundraising success

From the outset, support for the Fund was immense. Within the first year, over $1 million was raised through community donations and the inaugural Stefanie Spielman Classic golf tournament. Excitement grew as fundraising records continued to be shattered.

By 2009, total money raised had surpassed $10 million. Landmark gifts like a $3.3 million donation from the Rainbow Babies & Children’s Hospital Foundation fueled rapid expansion. Momentum kept building even after Stefanie’s passing, affirming the resonance of her inspirational legacy.

Milestones motivating ongoing support

In 2011, James Cancer Hospital announced a $10 million naming gift from Leslie Wexner for the Stefanie Spielman Comprehensive Breast Center. This tangible representation of progress continues to motivate donors today.

The Fund also surpassed $15 million raised in 2011 and reached $20 million by 2014. Stefanie’s 40th birthday in 2013 aligned with launching the Champions luncheon which has generated over $2 million so far.

Exceeding $25 million raised marked a major milestone in 2018, further cementing the Fund’s reputation as a trusted steward of resources to combat breast cancer.

Multi-faceted fundraising strategy

The Fund’s comprehensive fundraising approach engages donors through diverse channels. Signature events like the Spielman Classic golf tournament, Champions luncheon, and birthday tributes foster community bonding.

Meanwhile, online donations provide an accessible outlet for individual supporters to give in honor of special occasions. Workplace giving expands the donor network through payroll deductions.

Corporate partnerships with the likes of Huntington Bank, Nationwide Insurance, and Safelite AutoGlass integrate philanthropy into business models. Collectively, these strategies enlarge the funding pool to accelerate progress.

Funding the future

While Stefanie Spielman tragically lost her battle with breast cancer, her selfless legacy lives on through the Fund advancing groundbreaking research in her name. Because of the $25 million raised so far, scientists are unraveling breast cancer’s weaknesses to develop targeted prevention strategies.

Moving forward, the Fund will continue pioneering creative fundraising initiatives to propel scientific discovery. There is a future on the horizon where no one will endure the devastation of a breast cancer diagnosis, thanks to Stefanie’s enduring spirit and the compassion of thousands united in securing a lasting legacy of hope.

Join the effort to support and empower breast cancer research

Breast cancer remains a pressing health crisis, with over 300,000 invasive diagnoses annually in the U.S. alone. Yet there is hope on the horizon thanks to organizations like the Stefanie Spielman Fund for Breast Cancer Research tirelessly seeking strategies to eradicate this disease.

By supporting the Fund, donors empower groundbreaking science that will unlock breast cancer’s secrets and stop it before it ever starts. There are many meaningful ways to contribute and become part of Stefanie’s inspirational legacy.

Donate to fund future breakthroughs

Direct donations provide flexible funding for pioneering projects most likely to lead to breakthroughs. Recurring monthly or annual gifts ensure researchers have stable resources to pursue promising work.

Tribute donations in honor of milestones like birthdays or anniversaries celebrate loved ones while contributing to progress. Planned estate gifts allow donors to make a lasting impact beyond their lifetime.

Participate in signature fundraising events

The Fund’s cornerstone events, like the Stefanie Spielman Classic golf tournament and Stefanie’s Champions luncheon, unite communities around Stefanie’s mission while raising critical funds.

Groups can also organize their own third party events, from charity races to volleyball tournaments to cocktail parties. This allows creative freedom to honor Stefanie while collecting donations.

Explore workplace giving programs

Payroll deduction through employers makes donating easy and tax-efficient. Ohio State faculty have given over $1 million so far through the university’s workplace campaign. Exploring whether your company offers a matching gifts program can double your impact.

Spread awareness on social media

Social media enables supporters to easily share information about the Fund’s groundbreaking research and how to get involved. Tagging the Fund’s accounts spreads inspiring stories to new audiences.

Updating your Facebook profile to the “No One Should Face Breast Cancer Alone” frame during October’s Breast Cancer Awareness Month builds a supportive online community.

Advocate to accelerate progress

Donors can maximize impact by advocating to government representatives about the urgent need for research funding. Joining advocacy groups like the National Breast Cancer Coalition mobilizes an influential collective voice.

Carry on Stefanie’s uplifting legacy

While breast cancer cruelly cut Stefanie Spielman’s life short, her bright spirit lives on through the Fund’s determined efforts to eradicate this disease. By supporting the Fund that bears her name, donors help ensure breakthroughs are within reach.

Each donation, event, and act of advocacy brings us one step closer to realizing Stefanie’s dream that no one should face the devastation of breast cancer ever again. Together, we can empower research that saves lives for generations to come.